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Current status of diabetes, hypertension and dyslipidemia among older Chinese adults in Update on the development of enterovirus 71 vaccines. The data for a total of males and females participants were included in the analysis.
Trained neurologists evaluated each participant’s cognitive function with the Mini-Mental State Examination MMSEwhich is a commonly used measurement worldwide. The baseline characteristics of the participants are shown in Table 1. Table 2 Association between the prevalence, treatment and control of hypertension and the MMSE score by gender. A Taiwan study showed that EV71 can be detected in the throat up to 2 weeks after recovery from HFMD or herpangina, and can be detected in stool samples up to 11 weeks after recovery Seventh report of joint national committee on prevention, detection, evaluation, and treatment of high blood pressure.
Table 4 Association between the prevalence, treatment and control of hypertension and the prevalence of MCI by age. Most deaths caused by pulmonary hemorrhage in patients with EV71 brainstem encephalitis usually occur within 24 hours after admission because the disease rapidly progresses to the critical stage 2 The association of antihypertensive medication use with risk of cognitive decline and denmentia: The first major EV71 outbreak in the Asia-Pacific region occurred in in Malaysia and caused 41 child deaths 6.
Enterovirus 71 infection and neurological complications
Ageing Res Rev ; Vascular risk and cognitive ve in an older, British, African-Caribbean population. The results demonstrated the high safety and immunogenicity of the EV71 vaccines.
Trained observers calculated the average of the three records as the final measurement. Less Alzheimer disease neuropathology in medicated hypertensive than nonhypertensive persons. In regard to the long-term outcome, one study conducted follow-up of children after EV71 infection with CNS involvement, including 28 cases of cardiopulmonary failure median follow-up of 2. Therefore, during EV71 epidemics, the neurological complications of EV71 infection should always be considered in children who develop neurological diseases, even ej patients 1999 no skin lesions characteristic of HFMD.
Overall, participants in all age groups showed trends that were similar to those of the general population.
Seroepidemiology of Enterovirus 71 infection prior to the season in children in Shanghai. In Korea, epidemics of EV71 infection occurred between and and included fatal cases. Human P-selectin glycoprotein ligand-1 is a functional receptor for 99882 Clinico-radiological spectrum in enterovirus 71 infection involving the central nervous system in children.
It usually presents like poliomyelitis with acute motor weakness of the extremities, but unlike poliomyelitis, the recovery rate is relatively high 2.
Table 3 Association between the prevalence, treatment and control of hypertension and the prevalence of MCI by gender.
Enterovirus 71 infection and neurological complications
Since then, large-scale epidemics of EV71 have been reported in many Asia-Pacific countries including Taiwan, Australia, China, Singapore, Vietnam, and Cambodia, and have caused many fatalities 7891011919913 As the most important risk factor for stroke, hypertension substantially increases the risk of cognitive impairment. Update of enterovirus 71 infection: Notes The authors declare no conflict of interest.
According to one report 22which compared the viral pathogens and clinical features of Fe between and in Korea using data from a nationwide surveillance system, the main causative viruses were coxsackievirus A10 and echovirus 30 inwhereas the chief pathogen in pei EV The prevalence of MCI was higher in hypertensive EV71 can be transmitted via contaminated hands; either directly from vesicles on the hands, secretions from the oropharynx, or feces In patients with acute flaccid paralysis, MRI typically shows high-signal lesions in the anterior horn cells of the spinal cord on T2-weighted images, and contrast enhancement in the ventral root on Sm images Fig.
Some studies have noted that aseptic meningitis is the most common neurological complication of EV71 infection 3040although many other studies have reported brainstem encephalitis as the most common neurological complication 24 MRI findings of neurological complications The characteristic MRI findings of EV71 brainstem encephalitis are high signal intensities on T2-weighted and fluid-attenuated inversion ee images in the posterior region of the pons, medulla oblongata, midbrain, and bilateral dentate nuclei of the cerebellum Fig.
Effects of blood pressure lowering with perindopril and in dapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Since the outbreak of the enterovirus 71 EV71 infection in Malaysia inlarge epidemics of EV71 have occurred in the Asia-Pacific region. The association between hypertension and MCI Table 3 shows the unadjusted and adjusted associations 19999 the prevalence, treatment and control of 19999 and the prevalence of MCI by gender.
However, EV71 can cause more severe neurological complications compared with other enterovirus serotypes, including brainstem encephalitis and acute flaccid paralysis 2 Vascular risk factors and cognitive disorders. Prevalence, awareness, treatment, and control of hypertension in china.
llei Development of enterovirus 71 vaccines. During EV71 epidemics, the neurological complications of EV71 infection always should be considered in the differential diagnosis in children with neurological diseases.
Genetic analysis of enterovirus 71 isolated from fatal and non-fatal cases of hand, foot and mouth disease during an epidemic in Taiwan,