ALIMTA PACKAGE INSERT PDF

ALIMTA (pemetrexed for injection) [package insert]. Indianapolis, IN: Eli Lilly and Company; Langer CJ, et al. Lancet Oncol. ;17(11) Learn how ALIMTA may help treat advanced nonsquamous non-small cell lung cancer. ALIMTA and carboplatin (carbo) is approved by the FDA to be used with an the FDA in combination with carboplatin (another chemotherapy drug) and. Read all of this leaflet carefully before you start receiving this medicine because it contains important information for you. -. Keep this leaflet. You may need to.

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If concomitant ibuprofen use cannot be avoided, monitor patients more frequently for ALIMTA adverse reactions, including myelosuppression, renal, and gastrointestinal toxicity. Based on findings from animal studies and its mechanism of action, ALIMTA can cause fetal harm when administered to a pregnant woman.

ALIMTA® (pemetrexed): Storage of Unreconstituted Vials

Adverse reactions observed in pediatric patients studied were similar to those observed in adults. ALIMTA is indicated, in combination with cisplatin, for the initial treatment of patients with malignant pleural inseert MPM whose disease is unresectable or who are otherwise not candidates for curative surgery.

Eli Lilly and Company; Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

Scagliotti GV, et al. Talk to your healthcare provider if this is a concern for you. This may affect your ability to father a child. Continued approval for this indication may be contingent upon verification and description of clinical benefit in the confirmatory trials.

Tell your healthcare provider right away if you packgae a decrease in amount of urine. Advise pregnant women of the potential risk to the fetus.

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Advanced NS NSCLC Treatment | ALIMTA (pemetrexed for injection)

Kidney problems, including kidney failure. The risk of myelosuppression is increased in patients who do not receive vitamin supplementation. Advise males with female partners of reproductive potential to use effective contraception during treatment with ALIMTA and for 3 months after the final dose.

This indication is approved under accelerated approval based on tumor inser rate and progression-free survival. Based on Kaplan-Meier estimation. It is not known if these effects are reversible.

ALIMTA® (Pemetrexed) and Pharmacokinetics

Obtain a complete blood count at the beginning of each cycle. The infusion is given over 10 minutes.

Tell your healthcare provider about all of the medicines you take, alimfa prescription and over-the-counter medicines, vitamins, and herbal supplements. NCCN makes no warranties of any kind whatsoever regarding their content, use, or application and disclaims any responsibility for their application or use in any way. Tell your healthcare provider right away if you have any signs of infection, fever, bleeding, or severe tiredness during your treatment with ALIMTA.

Indications and Important Safety Information.

Males of Reproductive Potential: Monitor patients for inflammation or blistering in areas of previous radiation treatment. There is no information regarding the presence of pemetrexed or its metabolites in human milk, the effects on the breastfed infant, or the effects on milk production.

ALIMTA® (pemetrexed): Storage of Unreconstituted Vials

Tell your healthcare provider right away if you develop blisters, skin sores, skin peeling, or painful sores, or ulcers in your mouth, nose, throat or genital area.

Radiation recall is a skin reaction that can happen in people who have received radiation treatment in the past and are treated with ALIMTA. To view the most recent and complete version of the guidelines, go online to NCCN.

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Low blood cell counts can be severe, including low white blood cell counts neutropenialow platelet counts thrombocytopeniaand low red blood cell counts anemia. The incidences of Grade anemia, fatigue, thrombocytopenia, hypertension, and neutropenia were higher in patients 65 years of age and older as compared to younger patients: Advise females of reproductive potential to use effective contraception during treatment with ALIMTA and for 6 months after the final dose.

It is not known whether these effects on fertility are reversible. Low blood cell counts.

Hold on longer to what matters most. Tell your healthcare provider if you have kidney problems and take a medicine that contains ibuprofen. Tell your healthcare provider right away if you get any new or worsening symptoms of shortness of breath, cough, or fever.

ALIMTA is contraindicated in patients who have a history of severe hypersensitivity reaction to pemetrexed. Accessed June 27, Your healthcare provider will prescribe a medicine called a corticosteroid for you to take 2 times a day for 3 days, beginning the day before each treatment with ALIMTA. ALIMTA is indicated as a single agent for the maintenance treatment of patients with locally advanced or metastatic nonsquamous non-small cell lung cancer NSCLC whose disease has not progressed after four cycles of platinum-based first-line chemotherapy.

You are encouraged to report negative side effects of prescription drugs to the FDA. Patients with Renal Impairment: Go to data for additional indications. Your healthcare provider will do a blood test to check your blood cell counts regularly during your treatment with ALIMTA.

For more information, ask your healthcare provider or pharmacist.